|
|
Article: Epidemiologic Studies Suggest Genetic Predisposition.(suicidal behavior )
- Article from:
- Genomics & Genetics Weekly
- Article date:
- April 20, 2001
CopyrightCOPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
2001 APR 20 - (NewsRx.com & NewsRx.net) -- A specific genetic vulnerability for suicidal behavior is strongly suggested by the results of epidemiological genetics studies. Several lines of evidence suggest that regulation of serotonin neurotransmission is a key factor for this vulnerability.
Recent studies have investigated the involvement of the gene coding for the tryptophan hydroxylase (TPH), the rate-limiting enzyme in serotonin biosynthesis, in the genetic susceptibility to suicidal behavior.
In a case-control study, reported in the April 2001 issue of Molecular Psychiatry, M. Abbar et al. investigated seven polymorphisms spanning the entire TPH ...