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Article: Intrasellar Pituicytoma in a Patient With Other Endocrine Neoplasms.
- Article from:
- Archives of Pathology & Laboratory Medicine
- Article date:
- April 1, 2001
- Author:
CopyrightCOPYRIGHT 2001 College of American Pathologists. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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The posterior lobe of the pituitary gland or neurohypophysis contains unique glial elements referred to as pituicytes. These cells play a supportive role for the axons of large vasopressin and oxytocin-producing neurons whose cell bodies reside in the hypothalamus.[1] Among neoplasms that arise from the neurohypophysis, intrasellar granular cell tumors are best known and may originate from pituicytes.[2] In addition, very rare low-grade spindle cell tumors,[3-6] claimed to represent pituicytomas and thought to arise from pituicytes, are encountered along the neurohypophysis. The morphologic features of these tumors are distinct, but their immunophenotype is somewhat ...