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Article: Nasal Mucosa Generates Accurate Correlation With Allergen Exposure.
- Article from:
- Immunotherapy Weekly
- Article date:
- May 16, 2001
CopyrightCOPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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2001 MAY 16 - (NewsRx.com & NewsRx.net) --
by Deborah W. Heinrich, PhD, staff medical writer - Researchers at the University of Perugia in Italy found that immunoglobulin E (IgE) and eosinophil cationic protein (ECP) levels in the nasal mucosa more accurately correlated with allergen exposure than IgE and ECP levels in serum.
F. Marcucci and colleagues hypothesized that monitoring immune reactions in the primary organ of exposure would be a more accurate method for monitoring allergic reactions. They therefore used in situ hybridization to determine mast cell IgE concentrations and ECP levels in the nasal mucosa and serum of 26 patients with grass ...