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Article: Early Withdrawal of Immunosuppressive Drugs Possible.

Article from:
Blood Weekly
Article date:
July 5, 2001
Copyright

2001 JUL 5 - (NewsRx.com & NewsRx.net) --

To minimize the risk of acute rejection during the first months after transplantation it is common practice in most transplant centers to use a combination of immunosuppressive agents. In the longer term, however, increasing emphasis is placed on dose reduction or withdrawal of adjunctive immunosuppressants, with the aim to reduce the risks of over-immunosuppression and the number of side effects of therapy.

Clear evidence that corticosteroids or mycophenolate mofetil (MMF) can be withdrawn at three months from a triple therapy regimen, consisting of the cornerstone immunosuppressant tacrolimus (Prograf) combined ...

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