Article: WHITEHEAD SCIENTISTS DRAGOON 'OBSCURE' CARBON CYCLE TO CUT CANDIDA VIRULENCE DOWN TO SIZE.(Whitehead Institute for Biomedical Research)(Brief Article)

For sheer diabolicity, Candida albicans would be hard to beat. When this life-threatening fungus infects the heart, it can cause endocarditis, which often means replacing the infected heart valve. But C. albicans has a special sweet tooth for medical plastics, and goes right to work devouring the replacement valve.

"Our ability to treat someone with a fungal infection is poor at best," observed molecular biologist Michael Lorenz, at the Whitehead Institute for Biomedical Research in Boston. "Physicians have been reluctant to date to give antifungal drugs as prophylaxis. That is changing; more and more people are coming down with fungal infections - ...

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