Article: Evidence of an Inflammatory Pathologic Condition in "Normal" Appendices Following Emergency Appendectomy.

Despite the fact that acute appendicitis is the most common surgical emergency, it continues to be a challenging disease.[1,2] The practice of early appendectomy for clinically suspected appendicitis has resulted in decreased morbidity, but both surgeons and pathologists are aware that a significant proportion of appendices that are removed show no evidence of inflammation.[3-9] This discrepancy between clinical presentation and the lack of definite morphologic changes is confounding. Since appendectomy relieves symptoms in most of these patients, it is likely that an as yet unknown causative pathologic condition exists in the appendices of these patients. Some recent ...

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