|
|
Article: Antibody Targets Amyloid-Beta Protein.(Alzheimer disease)
- Article from:
- Immunotherapy Weekly
- Article date:
- August 8, 2001
CopyrightCOPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
2001 AUG 8 - (NewsRx.com & NewsRx.net) --
Researchers at Washington University School of Medicine in St. Louis, Missouri, and Eli Lilly and Co. have new data from a mouse study that may explain why certain antibodies can slow or reverse changes in the brain that are characteristic of Alzheimer disease.
The preclinical study used an antibody that targets a particular region on the amyloid-beta protein. The amyloid-beta protein accumulates in the brain to form the amyloid plaques, a major characteristic of Alzheimer disease.
"We think the antibody is drawing amyloid-beta out of the brain and into the blood as a clearance mechanism," said senior ...