Article: Alternative to Routine Amniocentesis Proposed.

MAUI, HAWAII -- A three-pronged strategy to screen for fetal abnormalities using two ultrasound examinations and triple-marker serum screening may be safer and less expensive than routinely offering amniocentesis to older women, Dr. Manuel Porto said at a conference on ob.gyn. ultrasound sponsored by the University of California, Irvine.

In a hypothetical group of 10,000 pregnant women aged 35 or older, the triad of tests would be half as expensive as routine amniocentesis (saving almost $5 million), cause half as many deaths in normal fetuses (24 instead of 50), and would miss few cases of serious aneuploidy, he said.

Routine amniocentesis would detect ...

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