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FISH Alternative Promising for Aneuploidy Search.
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OB GYN News
- Article date:
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August 1, 2001
- Author:
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Copyright informationCOPYRIGHT 2001 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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RANCHO MIRAGE, CALIF. -- A relatively new technique called comparative genomic hybridization may soon replace fluorescent in situ hybridization as the method of choice for obtaining preimplantation genetic diagnoses for aneuploidy in blastomeres.
Comparative genomic hybridization (CGH) is a molecular cytogenic technique that enables simultaneous enumeration of every chromosome, in contrast to fluorescent in situ hybridization (FISH), which at present can karyotype only a maximum of nine chromosomes, Leeanda Wilton, Ph.D., said at the annual meeting of the Pacific Coast Reproductive Society.
The technique was originally developed to look for aneuploidies in tumor cells. ...
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