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Article: Diagnostic Utility of Intracytoplasmic Lumen and Transgressing Vessels in Evaluation of Hurthle Cell Lesions by Fine-Needle Aspiration.(Statistical Data Included)
- Article from:
- Archives of Pathology & Laboratory Medicine
- Article date:
- August 1, 2001
- Author:
CopyrightCOPYRIGHT 2001 College of American Pathologists. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Hurthle cells are thyroid follicular cells with abundant granular cytoplasm. Hurthle cell nodules of the thyroid can result from nonneoplastic conditions such as Hashimoto's thyroiditis, adenomatous goiter, and Graves' Disease.[1] Conversely, neoplastic nodules may be composed of Hurthle cells. Although Hurthle cells can be readily identified by their unique cytomorphology in thyroid fine-needle aspirates (FNAs), the cytologic distinction of Hurthle cell neoplasms (HCNs) from nonneoplastic lesions with prominent Hurthle cells may be difficult. Hurthle cell atypia associated with Hashimoto's thyroiditis can lead to a false diagnosis of HCN.[2-4] Accurate diagnosis of HCN ...