Article: Diuretic Cuts Cost, Dose of Angiotensin Receptor Blocker.(hydrochlorothiazide)

The combination of an angiotensin receptor blocker plus hydrochlorothiazide is a more cost-effective treatment for hypertension than an angiotensin receptor blocker alone, Daniel E. Hilleman, Pharm.D., said in a poster presentation at the annual meeting of the American Society of Hypertension.

Investigators analyzed data on 3,883 patients from 14 randomized, controlled trials that evaluated three commercially available fixed-dose combinations of hydrochlorothiazide and an angiotensin receptor blocker (ARB)--losartan, telmisarran, or valsartan. They calculated cost-effectiveness using annual average wholesale prices and pooled estimates of blood pressure ...






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