Article: Scientists Determine Molecular Structure Of A Metallochaperone Bound To Its Target Protein.(research on the cause of amyotrophic lateral sclerosis and other nervous system disorders)

2001 SEP 15 - (NewsRx.com & NewsRx.net) --

A breakthrough by scientists at Northwestern University could advance understanding of the biochemical causes of some nervous system disorders, including forms of amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease.

A team led by Amy Rosenzweig, assistant professor of biochemistry, molecular biology and cell biology and of chemistry, in collaboration with Thomas O'Halloran, professor of chemistry, is the first to determine the molecular structure of a metallochaperone (a protein that delivers metals to enzymes that need them to function) bound to its target protein.

Specifically, the ...

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