Article: Selected abstracts (*). (SPECIAL FEATURE).(sleep-disordered breathing and apolipoprotein E)(statin therapy)(thyroxine in hormone therapy)(transdermal fentanyl for pain)(vision impairment and accidental falls)

ASSOCIATION BETWEEN APOLIPOPROTEIN E [member of]4 AND SLEEP-DISORDERED BREATHING IN ADULTS

Kadotani H, Kadotani T, Young T, et al. JAMA 2001; 285:2888-2890

A significant portion of sleep-disordered breathing is associated with Apo[member of]4. This longitudinal cohort study of sleep disorders was conducted at a US university in 1989, providing a population-based probability sample of 791 middle-aged adults (mean {SD} age, 49 {8} years; range, 32-68 years). The probability of moderate-to-severe sleep-disordered breathing (apnea-hypopnea index [greater than or equal to] 15%) was significantly higher in those with [member of]4, independent of age, sex, body ...

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