Article: Researchers Identify Enzyme Responsible For Genetic Diversity.(Brief Article)

2001 DEC 5 - (NewsRx.com & NewsRx.net) -- Simultaneous reports by two teams at the Scripps Research Institute (TSRI), led by Professor Paul Russell, PhD, and Associate Professor Clare H. McGowan, PhD, identify the resolvase enzyme that may be responsible for generating genetic diversity during sexual reproduction and could be a target for improved anticancer therapy.

In the journals Cell and Molecular Cell, the researchers have published papers that describe Mus81, a resolvase enzyme of the fission yeast Schizosaccharomyces pombe, and its human analog.

Resolvase is essential for a crucial step in DNA recombination, says Russell, because it is the ...

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