Article: Celgene Corp. Issued Additional U.S. Patent For IMiD Pipeline.(immunomodulatory drug patent)

2001 DEC 26 - (NewsRx.com & NewsRx.net) -- Celgene Corp. has been issued U.S. Patent No. 6,316,471, which covers the use of Actimid (CDC 394), Celgene's next IMiD (immunomodulatory drug), to treat cancer and inflammatory diseases both as a single agent and in combination with other therapies. The patent also covers the pharmaceutical compositions of Actimid.

Actimid was found to be well tolerated in a single-blind, placebo-controlled, ascending dose Phase I trial in 30 healthy volunteers. Importantly, sedation, which can be an undesirable side effect of thalidomide, was not detected in this trial. Actimid is currently being evaluated as a treatment for ...

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