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Article: NIH 7-Day On-Off Trial May Reduce Drug Side Effects, Cost; Why It's Not Ready for Use.(National Institutes of Health antiretroviral study)
- Article from:
- AIDS Treatment News
- Article date:
- December 21, 2001
- Author:
CopyrightCOPYRIGHT 2001 John S. James. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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On December 4 researchers at the U.S. National Institute of Allergy and Infectious Diseases published an early report of their 7-day-on/7-day-off trial of antiretrovirals. (1) This study found that a handful of selected patients, with a selected antiretroviral regimen, were able to use the drugs intermittently, with a schedule of 7 days on and 7 days off. They were able to maintain viral suppression for 32-68 weeks so far, with only half the drug use and clearly reduced side effects. The researchers emphasize that this regimen is not ready for use outside of controlled clinical trials. The reasons are explained in the article, but not in most news reports.
The ...
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