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Article: Bronchial carcinoid tumor with crystalloid cytoplasmic inclusions.
- Article from:
- Archives of Pathology & Laboratory Medicine
- Article date:
- January 1, 2002
- Author:
CopyrightCOPYRIGHT 2002 College of American Pathologists. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Since the initial description of bronchial carcinoid tumors by Hamperl in 1937, (1) many histologic variations have been described, including a diversity of architectural forms, such as insular, trabecular, rosette-forming, pseudoglandular, solid, and papillary. Despite this growth pattern variability, most of these tumors have in common cytologically bland, round cells with stippled chromatin and a moderate amount of granular eosinophilic cytoplasm. (2,3)
The granularity of the cytoplasm in carcinoid tumors in most cases is related to the presence of neurosecretory granules, although rare cases of oncocytic carcinoids with an abundance of mitochondria have been ...