Article: Cephalon Files Application Seeking Additional Indication For PROVIGIL in the United Kingdom; Obstructive Sleep Apnea Clinical Trial Data Submitted for Review to UK Medicines Control Agency (MCA).

WEST CHESTER, Pa. -- Cephalon, Inc. today announced that it has filed a Marketing Authorization Application (MAA) in the United Kingdom to expand the label of PROVIGIL(R) (modafinil) to treat excessive daytime sleepiness in patients with obstructive sleep apnea. PROVIGIL was launched in the U.K. for the treatment of narcolepsy in March 1998.

This application was filed on the basis of positive data generated from two studies of PROVIGIL tablets in more than 480 patients with obstructive sleep apnea. The results of these studies indicate that PROVIGIL may be a useful adjunctive treatment for excessive daytime sleepiness in patients with obstructive sleep apnea ...

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