Article: The preparation of new dihydronaphthisoxazoles using strong-base multiple anion synthesis methodology.(Brief Article)

The purpose of the project is to use strong-base synthesis to produce compounds that cannot be produced by traditional methods and are not commercially available. These compounds are prepared by adding lithium diisopropylamide (LDA) to an oxime; this solution is tirred for 45 minutes. Alter this 100 mi of 3-nyhdrocholoric acid is added and heated under reflux for 45-60 minutes. Then the solution is ...

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