Article: Twice-weekly therapy not enough for co-infected, CDC says in advisory; changes will add `significant expense'.(Centers for Disease Control and Prevention)(Brief Article)

TB patients with HIV and severe immune depression need daily therapy initially, and therapy three times weekly during the second phase of treatment, federal TB experts have decided. Otherwise, they may develop rifamycin resistance, according to surprising evidence from a new study.

The new directive issued by the Centers for Disease Control and Prevention's Division of TB Elimination (DTBE) is in effect at least until more data become available on the study findings, according to the Morbidity & Mortality Weekly Report for March 15, 2002. (1)

The new recommendation may pose a hardship for TB control programs already strapped for time and money. Many ...

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