Article: Blood levels of long-chain n-3 fatty acids and the risk of sudden death.(Abstract)

Alberta CM, Campos H, Stamper MJ, et al. N Engl J Med 2002;346:1113-1118.

BACKGROUND: Experimental data suggest that long-chain n-3 polyunsaturated fatty acids found in fish have antiarrhythmic properties, and a randomized trial suggested that dietary supplements of n-3 fatty acids may reduce the risk of sudden death among survivors of myocardial infarction. Whether long-chain n-3 fatty acids are also associated with the risk of sudden death in those without a history of cardiovascular disease is unknown. METHODS: We conducted a prospective, nested case-control analysis among apparently healthy men who were followed for up to 17 years in the Physicians' Health ...

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