Article: Pharmacogenomics has emerging role in today's clinical practice.

PHILADELPHIA, Pennsylvania--The use of clinical laboratory tests to guide drug therapy has been an established aspect of medicine for over two decades, emerging as a separate discipline within the laboratory in the late 1970s with the introduction of tests for therapeutic drug monitoring such as the Syva EMIT assays. The market for such tests has matured, with sales estimated at about $190 million in the U.S. in 2001 and growth at about 6% per year. Serum drug levels are routinely monitored for only about 20 therapeutic drugs at present, with immunosuppressants the most widely monitored, and drugs such as phenytoin also routinely measured. One limitation of existing ...

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