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Article: Bone marrow stem cells involved in pathogenesis.
- Article from:
- Blood Weekly
- Article date:
- August 22, 2002
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2002 AUG 22 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Hematopoietic stem cells may play a key role in arthritis development, according to researchers in Japan.
"Recent studies have suggested the involvement of bone marrow in the pathogenesis of rheumatoid arthritis (RA), in which proliferation of monocyte-lineage cells (MLC) as well as local B cell activation in the synovium play an important role," explained Dr. Shunsei Hirohata and colleagues at Teikyo University in Tokyo and Osaka University in Osaka.
Hirohata and coauthors showed that, under the right conditions, bone marrow cells from RA patients can differentiate into ...