Article: The chemistry of despair. (anti-depressants) (Science and Technology)

SINCE its launch in America in 1987, an anti-depressant drug called Prozac (or fluoxetine) has been a phenomenal success. This year it could bring Eli Lilly, Prozac's American manufacturer, $675m from sales throughout the world. Most doctors have welcomed the drug because it is the first new treatment for depression in decades. It also has far fewer nasty side-effects than its predecessors had. Yet, although there have been many anecdotal reports of wondrous improvements, formal studies suggest that Prozac is no more effective than traditional anti-depressants. Happily, better things are on the way.

Everybody gets depressed at some time or other. Usually the mood ...

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