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Article: Genetic vaccine can protect against Chagas disease.
- Article from:
- Gene Therapy Weekly
- Article date:
- October 10, 2002
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2002 OCT 10 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A genetic vaccine against the parasite responsible for Chagas disease can protect animals from infection, researchers in the United States report.
"Immunity to Trypanosoma cruzi requires elicitation of humoral and cell-mediated immune responses to extracellular trypomastigotes and intracellular amastigotes," explained Nisha Garg and colleagues working at the University of Georgia in Athens.
Mice immunized with a key T. cruzi gene showed robust T-cell and antibody responses to infection, suggesting that a DNA-based approach can produce an effective vaccine for humans, ...