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Article: Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis) are independent of their alkaloid content.
- Article from:
- Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
- Article date:
- May 1, 2002
- Author:
CopyrightCOPYRIGHT 2002 Urban & Fischer Verlag. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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M. Sandoval (1), N. N. Okuhama (1), X.-J. Zhang (1), L. A. Condezo (2), J. Lao (2), F. M. Angeles (1), R. A. Musah (3), P. Bobrowski (4), and M. J. S. Miller (1)
Summary
Cat's claw is an herbal medicine from the Amazon that is used widely to treat inflammatory disorders. The purpose of this study was to characterize the antioxidative and antiinflammatory properties of cat's claw, Uncaria tomentosa (UT) and Uncaria guianensis (UG). Alkaloids and flavanols were determined using reversed-phase HPLC; scavenging of 1,1-diphenyl-2-picrilhydrazyl (DPPH), hydroxyl radicals, and lipid peroxidation by spectrophotometry; and TNF[alpha] production by ELISA. ...
<0.01). The total oxindole and pentacyclic alkaloid content of UT was 35-fold>