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Article: Estrogenic and cholinergic properties of the methanol extract of Ruellia praetermissa Sceinf. ex. Lindau (Acanthaceae) in female rats.
- Article from:
- Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
- Article date:
- January 1, 2002
- Author:
CopyrightCOPYRIGHT 2002 Urban & Fischer Verlag. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Summary
In search for alternative drugs with pharmacological profile to replace hormone replacement therapy, the effects of MeOH extract of Ruellia praetermissa on the uterus and gestation in rats was investigated. 350 mg/kg/day of extract from days 1-9, 1-17 and 9-17 respectively, resulted in increase of the number of implantation sites (56 to 64) and the percentage of implantation (68.6 [+ or -] 2.7 to 90.5 [+ or -] 0.5%). There was also an increase in body weight (1-9 and 1-17) followed by a slight decrease (154 [+ or -] 15.5 to 125 [+ or -] 10) in the body weight at term. The number and the mean value of corpora lutea per female decreased from 25.4 [+ or -] ...