Article: Movement disorders - limb movement and the basal ganglia.

Movement Disorders--Limb Movement and the Basal Ganglia

Movement Disorders and

Motor Control

One method of attaining inferences about the role of a brain structure in the control of movement is the association of that structure with impairments of function. Such association may take place through brain imaging [1] or pharmacologically. [2] For example, in Huntington's disease, there is enhanced activity in the dopaminergic system, [1] whereas in Parkinson's disease, there is a loss of dopaminergic cells in the substantia nigra, such that patients respond to dopamine agonists therepy. [2] However, inverences about basal ganglia function are ...

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