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Article: 'Virtual stomach' reveals pill's path.
- Article from:
- Drug Week
- Article date:
- November 22, 2002
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2002 NOV 22 - (NewsRx.com & NewsRx.net) -- Penn State mechanical engineers, working with medical and pharmaceutical researchers, have developed the first computer-generated "virtual stomach" to follow the path of extended-release tablets that are designed to remain in the stomach for hours while slowly releasing medicine.
The researchers note that, although many medications are prepared in extended-release form, the details of exactly how the pills break down and release medicine in the stomach are largely unknown. The new "virtual stomach" has shown that tablet motion and mixing are highly sensitive to the pill's location in the stomach and to the coordination ...