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Article: Biomatrix assay useful for testing therapeutic agents.
- Article from:
- TB & Outbreaks Week
- Article date:
- December 24, 2002
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2002 DEC 24 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have developed a novel assay for testing antimicrobial peptide agents.
"Peptides that exert antimicrobial activity in artificial media may lack activity within blood or other complex biological matrices," explained Michael R. Yeaman and colleagues working at the University of California at Los Angeles.
Yeaman and coauthors developed an ex vivo biomatrix assay that enables analysis of peptide therapy candidates in a relevant environment.
The researchers designed a complex fluid matrix made up of whole blood, plasma, and serum. ...