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Article: Insulin sensitivity associated with intramuscular long-chain fatty acyl-CoAs.(Brief Article)
- Article from:
- Diabetes Week
- Article date:
- December 30, 2002
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2002 DEC 30 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Morbidly obese patients who lost weight after gastric bypass surgery also experienced significant reductions in intramuscular long-chain fatty acyl-CoAs that may be involved in insulin resistance, according to researchers in the U.S.
"Increases in intramyocellular long-chain fatty acyl-CoAs (LCACoA) have been implicated in the pathogenesis of insulin resistance in skeletal muscle," commented Joseph A. Houmard and colleagues at East Carolina University and Yale University School of Medicine.
The investigators measured the levels of LCACoA in the quadriceps ...