Article: Antimicrobial resistance in Streptococcus pneumoniae, Taiwan. (Synopsis).

Taiwan has one of the highest levels of antibiotic-resistant pneumococcus in the world. Pneumococcal isolates not susceptible to penicillin first appeared in Taiwan in 1986; in 1995 an increase in the prevalence of nonsusceptibility to penicillins, extended-spectrum cephalosporins, trimethoprim-sulfamethoxazole, and macrolides as well as multidrug resistance began to be recognized. With the persistence of antibiotic selective pressure, resistance in some antibiotics reached a high plateau ([beta]-lactam antibiotics) or continued to increase (macrolides), while novel resistance fluoroquinolones) emerged in the last 3 years. Widespread distribution of some novel resistant ...

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