Article: Hemoglobin-based agent reduces need for transfusion during heart surgery.

2003 JAN 9 - (NewsRx.com & NewsRx.net) -- A phase II clinical trial conducted at Duke University Medical Center and five other U.S. institutions has shown that an agent made of purified human hemoglobin appears safe and may be effective when used instead of transfused human blood to replace blood lost during heart surgery.

If the benefits of the agent, known as hemoglobin raffimer, are proved in subsequent phase III clinical trials, physicians would not need to use as much donated blood during surgery, the researchers said. An estimated 20% of all human blood transfused in the U.S. is associated with heart surgery, so the Duke researchers believe that an efficient ...

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