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Article: Distant tumors can share a common clonal origin.
- Article from:
- Cancer Weekly
- Article date:
- February 4, 2003
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2003 FEB 4 - (NewsRx.com & NewsRx.net) -- Researchers from Germany performed "a clonal analysis of gliomatosis cerebri (GC), a rare disease characterized by diffuse, extensively infiltrating glial tumors of the central nervous system.
"Two females of the series were not informative in assays for X-chromosomal inactivation, and a polycytosine tract of the mitochondrial DNA (mtDNA) was tested as a clonal marker. Following fluorescent PCR, a fraction of human individuals shows several electrophoretic bands in normal tissues, some of which can be lost in corresponding glial tumors.
"Two male patients of our series fulfilled this prerequisite and were thus ...
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