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Article: Syndecan-1 is strongly expressed in the hair follicle.
- Article from:
- Cancer Weekly
- Article date:
- February 4, 2003
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2003 FEB 4 - (NewsRx.com & NewsRx.net) -- "Syndecan-1 is the prototypic member of a family of heparan sulfate-bearing cell surface proteoglycans that function in adhesion, cell-extracellular matrix interactions, migration, and proliferation.
"During embryogenesis, syndecan-1 expression in the epithelium is downregulated when the epithelium gives rise to motile mesenchymal cells, whereas mesenchymal syndecan-1 expression is upregulated during organ formation. In aggressive basal cell carcinomas, syndecan-1 expression is evident in the stroma," researchers in the United States report.
"Some neoplastic cells induce stroma to meet needs for growth, and it ...