Article: Adenylyl cyclase isoform expression increased in adrenal gland of diabetic rats.

2003 FEB 10 - (NewsRx.com & NewsRx.net) -- According to a study from Sweden, "The spontaneously diabetic Goto-Kakizaki rat harbors the same defects expressed in human type 2 diabetes. It is not clear, however, whether stress factors emanating from the adrenal glands are involved in causing the diabetic state. For that reason, the authors studied gland size and expression of adenylyl cyclase isoforms in adrenal glands from Goto-Kakizaki and normal rats."

"Goto-Kakizaki rat adrenals were found to weigh only about half as much as those of control rats," said Guida Maria Portela-Gomes and colleagues at the University of Uppsala and the Karolinska Institute. "This ...

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