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Article: Locally produced IGF-I contributes to regulation of repair process.
- Article from:
- Immunotherapy Weekly
- Article date:
- February 12, 2003
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2003 FEB 12 - (NewsRx.com & NewsRx.net) -- According to a study from Australia, "Systemic administration of growth hormone (GH) stimulates granulation tissue formation, increases collagen deposition, improves the breaking strength of incisional wounds, and decreases donor-site healing times in burn patients. The possible role for circulating IGF-I in mediating this effect of growth hormone has not been investigated.
"To assess the relative effects of systemic IGF-I and GH on dermal repair, incisional wounds were created on the backs of male Sprague-Dawley rats treated with GH, or IGF-I or a combination of GH and IGF-I.
"After 7 days of treatment, wound ...