Article: Connective tissue growth factor may play role in formation.

2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "connective tissue growth factor stimulates fibroblast proliferation and extracellular matrix deposition in many fibrotic disorders. The aim of our study was to determine the expression pattern of connective tissue growth factor in postoperative intra-abdominal adhesions.

"Adhesions were created in 46 Sprague-Dawley rats by complete dissection and resuturing of a peritoneal patch 2 cm in diameter, lateral from the midline incision. Animals were killed at postoperative days 3, 6, 9, 12, 15, 18, and 21; and the adhesions scored on a scale of 0 to 5. Tissue samples ...

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