Article: Detection efficiency of gamma rays through fatty tissue for the external detection of sentinel lymph nodes in breast cancer diagnosis.

ABSTRACT. The ability to detect gamma ray passage through fatty tissue has biomedical applications in the diagnosis of metastatic breast cancer. The uptake of a [Tc.sup.99m]-labeled sulfur colloid solution into the primary or sentinel lymph nodes (SLN) supplying the breast is one mechanism by which potential metastasis is being assessed. If [gamma]-rays from the decaying [Tc.sup.99m] could be measured externally, the invasiveness of this diagnostic procedure would be greatly reduced. Using a [Co.sup.57] source, this experiment assessed [gamma]-ray intensity attenuation through porcine fatty tissue for thickness up to 76 mm. The porcine tissue accounted for a significant ...

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