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Article: Creatine kinase activity is essential for full recovery.
- Article from:
- Heart Disease Weekly
- Article date:
- March 9, 2003
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2003 MAR 9 - (NewsRx.com & NewsRx.net) -- According to recent research in Spain, "To define the relation between the phosphoryl transfer via creatine kinase and the ability to recover from an ischemia-reperfusion challenge, the authors chemically inhibited creatine kinase activity with iodoacetamide (IAm) and then measured myocardial recovery after 2, 10, or 30 min of global ischemia followed by 30 min of reperfusion in the isolated, arterially perfused interventricular septa of the rabbit heart.
"During normoxia, IAm (0.5 M perfused for 15 min) did not by itself modify developed tension, maximal rate of tension development, or resting tension.
"In ...