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Article: Thiamine. (Monograph).
- Article from:
- Alternative Medicine Review
- Article date:
- February 1, 2003
CopyrightCOPYRIGHT 2003 Thorne Research Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Introduction
[ILLUSTRATION OMITTED]
Thiamine, also known as vitamin B1, is a water-soluble, B-complex vitamin necessary for metabolism of proteins, carbohydrates, and tats. Thiamine is involved as a cofactor in numerous enzymes, and is essential in every cell for ATP production via the Krebs cycle.
Biochemistry and Pharmacokinetics
Thiamine functions as a coenzyme in more than 24 enzymes, most importantly pyruvate dehydrogenase (for energy production in the Krebs cycle), transketolase (for lipid and glucose metabolism, production of branched chain amino acids, and production and maintenance of myelin sheath), and 2-oxo-glucarate ...