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Article: In vitro apatite formation is good screening test for in vivo bioactivity.
- Article from:
- Biotech Week
- Article date:
- March 19, 2003
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2003 MAR 19 - (NewsRx.com & NewsRx.net) -- A study from Japan has shown that "evaluating apatite formation in simulated body fluid is a good screening test for the in vivo bioactivity of materials."
S. Fujibayashi and colleagues, Kyoto University, "compared in vivo bioactivity with the in vitro apatite-forming ability of biomaterials. Granules of five kinds of P[subscript]2O[subscript]5-free Na[subscript]2O-CaO-SiO[subscript]2 glasses, showing different apatite-forming ability in simulated body fluid (SBF), were implanted into a defect on the femoral condyle of rabbits. Bone ingrowth was evaluated using scanning electron microscopy among five kinds of glasses ...