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Article: History of HRT use tied to fewer bone metastases. (Breast Cancer Patients).
- Article from:
- OB GYN News
- Article date:
- March 15, 2003
- Author:
CopyrightCOPYRIGHT 2003 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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SAN ANTONIO -- Women who have been on hormone replacement therapy before being diagnosed with breast cancer have a significantly reduced incidence of bone metastases, Dr. Ingo J. Diel said at a breast cancer symposium sponsored by the San Antonio Cancer Institute.
"Our hypothesis is that healthy bone with normal bone turnover provides an infertile soil for tumor-seeding cells ... We believe that with HRT, like other osteoprotective therapies, we treat the soil for seeding tumor cells," explained Dr. Diel, an ob.gyn. at the University of Heidelberg (Germany).
He retrospectively reviewed 1,160 patients in whom breast cancer was diagnosed at age 45-70 ...