Article: Study confirms value of family-history knowledge for young women.(breast cancer genetics)(Brief Article)

2003 APR 17 - (NewsRx.com & NewsRx.net) -- A U.K. study published as a research letter in a leading medical journal highlights the importance of detailed family-history knowledge to help identify women with pathogenic gene mutations for breast cancer.

Women who carry mutations of BRCA1 and/or BRCA2 genes have a much higher lifetime risk of breast cancer - up to 80% - compared with noncarriers. A family history of breast cancer can be an indication of BRCA1/BRCA2 status.

Fiona Lalloo from St. Marys Hospital, Manchester, U.K., and colleagues assessed BRCA1/BRCA2 status and detailed family history for young women (aged 30 years or younger) in northwest ...

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