Article: Thyroid Gland

Thyroid Gland

The thyroid gland, the largest of the endocrine glands, is located in the neck just below the thyroid cartilage of the larynx . It consists of two lobes, one on either side of the trachea, joined by a narrow band or isthmus. It is composed of numerous hollow ball-shaped follicles with small, interspersed clusters of parafollicular cells.

Follicle cells concentrate and attach iodine to the amino acid tyrosine, producing two forms of thyroid hormone (TH): thyroxine or tetraiodothyronine (T 4 ), and smaller amounts of triiodothyronine (T 3 ). Manufacture and release of these hormones into the blood is regulated by thyroid stimulating hormone, TSH, from the pituitary gland. ...

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