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Article: Cortisone
- Article from:
- Chemistry: Foundations and Applications
- Author:
CopyrightCOPYRIGHT 2004 The Gale Group, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Cortisone
Cortisone is a steroid produced in the adrenal glands of the human body. The isolation of cortisone from the mixture of molecules produced in these glands was carried out by American biochemist Edward Kendall and coworkers. Kendall shared the Nobel Prize in physiology or medicine for this work in which he also helped establish the usefulness of cortisone in the treatment of arthritis.
The isolation of cortisone from adrenal glands is a laborious process, so its widespread utility as a medicine awaited the development of synthetic pathways to its production. Percy Julian was the first scientist to accomplish a commercially viable
synthesis
using protein from soybeans, and ...
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