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Article: Recombinant DNA

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Recombinant DNA

Recombinant DNA (rDNA) is made of segments of DNA (polymers of deoxyribonucleotides) from two or more sources. Nature has been recombining DNA in living cells for eons, but humans have only recently discovered the means to carry out this operation in the test tube. DNA is the molecule of heredity, and the procedure used for preparing rDNA is referred to as genetic engineering. The biotechnology industry and much of modern medicine, basic research, and agriculture depend on the use of rDNA.

How the Technology Developed

The discovery of restriction endonucleases, enzymes that reproducibly cleave double-stranded DNA molecules at specific sequences, paved the way for ...

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