Article: Thin Layer Chromatography

Thin Layer Chromatography

BRIAN HOYLE

Thin layer chromatography, which is typically abbreviated as TLC, is a type of liquid chromatography that can separate chemical compounds of differing structure based on the rate at which they move through a support under defined conditions.

TLC is useful in detecting chemicals of security concern, including chemical weapons, explosives, stabilizing chemicals for rocket propellants, and illicit drugs. For example, the Forensic Service Center of Lawrence Livermore National Laboratory has designed a computerized and portable TLC machine that can be taken to the field, and which has the ability to analyze 20 samples at a time. Analysis ...

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