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Article: Cancer
- Article from:
- Encyclopedia of Public Health
- Author:
CopyrightCOPYRIGHT 2002 The Gale Group Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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CANCER
Cancer is the end product of a multistep process (carcinogenesis) that occurs over many years. The term "cancer" actually refers to numerous distinct diseases characterized by abnormal cell growth and differentiation. Cancers are categorized by the organ and/or cell of origin. For example, squamous cell carcinoma of the lung arises from pulmonary epithelial tissue, whereas adenocarcinoma of the breast arises from mammary duct epithelium. The natural history of a cancer is highly dependent on the organ and cell type from which it is derived. In addition, prognosis is influenced by the stage and histologic grade of the cancer. Staging is generally designated by the TNM (tumor, ...