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Altretamine

Altretamine

Definition

Altretamine, also known by the brand name Hexalen, is an anticancer agent used to treat ovarian cancer .

Purpose

Altretamine is used to treat persistent or recurrent ovarian cancer, usually after treatment of the cancer with cisplatin and/or an alkylating agent fails to effectively treat the tumor.

Description

The mechanism of action of altretamine is not known. However, it is thought that it may inhibit DNA and RNA synthesis.

Recommended dosage

Alretamine is administered orally. Doses for the drug may be different depending on the protocol that is used by the physician. Some example dosing regimens are: 4 to 12 mg per kg in three to four divided ...

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